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The evidence that diet, physical exercise, and mental stimulation all help prevent age-related cognitive decline and reduce the risk of mild cognitive impairment and Alzheimer’s, is now very convincing.

Studies of mice and (rather intriguingly) beagles, have provided evidence that ‘enriched’ environments — ones that provide opportunities for regular exercise and mental stimulation — reduce or prevent age-related cognitive decline, and reduce the risk of Alzheimer’s.

I recently reported on a study showing how the gestures people made in describing how they solved a problem (the Tower of Hanoi) changed the way they remembered the game. These findings add to other research demonstrating that gestures make thought concrete and can help us understand and remember abstract concepts better.

Brain tissue is divided into two types: gray matter and white matter. These names derive very simply from their appearance to the naked eye. Gray matter is made up of the cell bodies of nerve cells. White matter is made up of the long filaments that extend from the cell bodies - the "telephone wires" of the neuronal network, transmitting the electrical signals that carry the messages between neurons.

The volume of gray matter tissue - a measure you will see cited in various reports - is a measure of the density of brain cells in a particular region.

Genes

Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.

Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).

Frances Yates described the memory strategy valued by the ancient Greeks and Romans as the "Art of Memory" in her widely quoted and seminal book The Art of Memory. Today we know it as the method of loci. But the Art of Memory, as those of the ancient world and those of the medieval world practiced it, is far richer than is implied by that title.

What is a tip-of-the-tongue experience?

The tip-of-the-tongue experience (TOT) is characterized by being able to retrieve quite a lot of information about the target word without being able to retrieve the word itself. You know the meaning of the word. You may know how many syllables the word has, or its initial sound or letter. But you can’t retrieve it all. The experience is coupled with a strong feeling (this is the frustrating part) that you know the word, and that it is hovering on the edges of your thought.

I talk a lot about how working memory constrains what we can process and remember, but there’s another side to this — long-term memory acts on working memory. That is, indeed, the best way of ‘improving’ your working memory — by organizing and strengthening your long-term memory codes in such a way that large networks of relevant material are readily accessible.

Oddly enough, one of the best ways of watching the effect of long-term memory on working memory is through perception.

In the education world, fixed mind-set is usually contrasted with growth mind-set. In this context, fixed mind-set refers to students holding the idea that their cognitive abilities, including their intelligence, are set at birth, and they just have to accept their limitations. With a growth mind-set, however, the student recognizes that, although it might be difficult, they can grow their abilities.

A growth mind-set has been associated with a much better approach to learning and improved academic achievement, but new research suggests that this difference has been over-stated.

In a 1987 experiment (1), readers were presented with a text that included one or other of these sentences:

or

Both texts went on to say:

We all like simple solutions. However much we may believe we are ‘above’ black-&-white dichotomies, that of course we understand that every situation is complex, nevertheless we have a brain that can only think of a very very few things at once. So it's unsurprising that we are drawn to solutions that can be summed up simply, that can fit comfortably within the limitations of working memory.