"Consolidation" is a term that is bandied about a lot in recent memory research. Here's my take on what it means.
Initially, information is thought to be encoded as patterns of neural activity — cells "talking" to each other. Later, the information is coded in more persistent molecular or structural formats (e.g., the formation of new synapses). It has been assumed that once this occurs, the memory is "fixed" — a permanent, unchanging, representation.
Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.
Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).
Dementia is estimated1 to afflict over 35.5 million people worldwide -- this includes nearly 10 million people in Europe, nearly 4.4 million in North America, nearly 7 million in South and Southeast Asia, about 5.5 million in China and East Asia and about 3 million in Latin America.
On my walk today, I listened to a downloaded interview from the On Being website. The interview was with ‘vocal magician and conductor’ Bobby McFerrin, and something he said early on in the interview really caught my attention.
Transfer refers to the ability to extend (transfer) learning from one situation to another. For example, knowing how to play the piano doesn’t (I assume) help you play the tuba, but presumably is a great help if you decide to take up the harpsichord or organ. Similarly, I’ve found my knowledge of Latin and French a great help in learning Spanish, but no help at all in learning Japanese.
We all like simple solutions. However much we may believe we are ‘above’ black-&-white dichotomies, that of course we understand that every situation is complex, nevertheless we have a brain that can only think of a very very few things at once. So it's unsurprising that we are drawn to solutions that can be summed up simply, that can fit comfortably within the limitations of working memory.
Around the world, for the most part, compulsory schooling starts at 6, although some start at 7, and a very few at 5 or even younger. There is less consensus about how long compulsory education should last, but 9 years is the most common length, with 10 years running a close second.
The conventional view of brain development has been that most of this takes place in utero and in the first three years, with the further development continuing until the brain is fully mature at around 10-12 years of age. The turbulence of adolescent behavior has been deemed to be mostly caused by hormonal changes. Piaget, who identified four stages of cognitive development, assessed that his highest stage — that of formal, abstract reasoning — occurred around 13-14 years (although not everyone reaches this level, which requires appropriate education).
Reading is a deceptive skill, for it is not a single process, but a number of processes. Thus, while you might be a fluent reader, in that you can swiftly and easily decode the letter-markings, and quickly access the meaning of the words, that doesn't mean you're a skilled reader of informational texts.
Let's look a little deeper into the value of mnemonics for knowledge acquisition. By “knowledge acquisition”, I mean the sort of information you learn from textbooks — information that is not personal, that you need for the long-term.
In this context, I believe the chief value of mnemonic strategies is to help you recall information that needs to be remembered in a particular order. Thus we use mnemonics to help us remember the order of the planets, the order of musical notes on the stave, the order of the colors in a rainbow.