Skip to main content

Articles

Genes

Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.

Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).

Let's look a little deeper into the value of mnemonics for knowledge acquisition. By “knowledge acquisition”, I mean the sort of information you learn from textbooks — information that is not personal, that you need for the long-term.

In this context, I believe the chief value of mnemonic strategies is to help you recall information that needs to be remembered in a particular order. Thus we use mnemonics to help us remember the order of the planets, the order of musical notes on the stave, the order of the colors in a rainbow.

Find out about the pegword mnemonic

Here are pegwords I've thought up in the Italian language.

As with the original example, let's try it out with our cranial nerves.

In italiano, sono i nervi cranici:

Find out about the pegword mnemonic

Here are pegwords I've thought up in the French language.

French pegword images

As with the original example, let's try it out with our cranial nerves.

En francais, les nerfs crâniens son:

I don't think anyone's going to try arguing that fruit and vegetables are not good for your health! We know they're good. But that's just general "oh, I know it's good for me" — do you know that the benefits are not only for your general health, your protection against obesity and diabetes, cancer and heart disease, but also for your brain. Actually, there's two aspects to this. An unhealthy diet (one rich in junk food, in saturated fat and sugar) is actively bad for your brain, and (the right) healthy diet is actively good for your brain.

There was an alarming article recently in the Guardian newspaper. It said that in the UK, diabetes is now nearly four times as common as all forms of cancer combined. Some 3.6 million people in the UK are thought to have type 2 diabetes (2.8 are diagnosed, but there’s thought to be a large number undiagnosed) and nearly twice as many people are at high risk of developing it. The bit that really stunned me? Diabetes costs the health service roughly 10% of its entire budget.

The Seattle Longitudinal Study of Adult Intelligence has followed a group of more than 5000 people for well over four decades. The program began in 1956 and participants have been tested across a whole gamut of mental and physical abilities at seven year intervals since that date.

The study has found:

"Consolidation" is a term that is bandied about a lot in recent memory research. Here's my take on what it means.

Becoming a memory

Initially, information is thought to be encoded as patterns of neural activity — cells "talking" to each other. Later, the information is coded in more persistent molecular or structural formats (e.g., the formation of new synapses). It has been assumed that once this occurs, the memory is "fixed" — a permanent, unchanging, representation.

I’ve recently had a couple of thoughts about flow — that mental state when you lose all sense of time and whatever you’re doing (work, sport, art, whatever) seems to flow with almost magical ease. I’ve mentioned flow a couple of times more or less in passing, but today I want to have a deeper look, because learning (and perhaps especially that rewiring I was talking about in my last post) is most easily achieved if we can achieve "flow" (also known as being ‘in the zone’).

Let’s start with some background.

I don't often talk about eyewitness testimony, but it's not because of the lack of research. It's a big field, with a lot of research done. When  I say I don't follow it because I regard the main finding as a done deal - eyewitness testimony is useless - that's not meant to denigrate the work being done. There is, clearly, a great deal of value in working out the exact parameters of human failures, and in working out how we can improve eyewitness testimony. I just arbitrarily decided to ignore this area of research until they'd sorted it all out!